Journal: Evidence-based Complementary and Alternative Medicine : eCAM
Article Title: Chai-Hu-San-Shen Capsule Ameliorates Ventricular Arrhythmia Through Inhibition of the CaMKII/FKBP12.6/RyR2/Ca 2+ Signaling Pathway in Rats with Myocardial Ischemia
doi: 10.1155/2022/2670473
Figure Lengend Snippet: Effect of CHSSC on the interaction between FKBP12.6 and RyR2 in ischemic H9C2 cells. (a) Co-immunoprecipitation was used to evaluate the interaction between FKBP12.6 and RyR2. (b) Quantitative analysis of the level of RyR2/FKBP12.6 in each group. N = 3 samples per group. All data are expressed as means ± SD. ∗ P < 0.05, ∗∗ P < 0.01, ∗∗∗ P < 0.001 vs. the control + H-89 group; # P < 0.05, ## P < 0.05, ### P < 0.001 vs. the model + H-89 group.
Article Snippet: Anti-FKBP12.6 (#sc-376135) was from Santa Cruz Biotechnology (Shanghai, China).
Techniques: Immunoprecipitation